Episode 426: Claude Cowork vs Microsoft 365 Copilot Cowork


Episode XXX

Episode Title goes here....

Hello Reader,

The next episode of the Microsoft Cloud IT Pro podcast has been released!

This week’s episode takes a closer look at a comparison that’s starting to come up more often: Claude Cowork vs Microsoft 365 Copilot Cowork.

While the names are similar, the way these tools work is very different.

Claude Cowork runs locally on your desktop, giving it direct access to your files and support for MCP server connections. Microsoft 365 Copilot Cowork, on the other hand, runs entirely in the cloud, with deep integration into Microsoft Graph and built-in compliance through Purview.

Here’s what we cover:

  • Local vs cloud-based AI workflows
  • File access and integration differences
  • MCP servers vs Microsoft Graph
  • Security and compliance considerations
  • When each tool makes the most sense

If you’re evaluating AI tools for your organization, this episode will help you understand the tradeoffs and where each option fits.

Listen to Episode 426 here: https://www.msclouditpropodcast.com/episode426/

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Show Notes

About the sponsors

TrustedTech is a leading Microsoft Cloud Solution Provider (CSP) specializing in Microsoft Cloud services, Microsoft perpetual licensing, and Microsoft Support Services for medium and enterprise-sized businesses. Our robust team of in-house, U.S-based Microsoft architects and engineers are certified in all 6/6 Microsoft Solutions Partner Designations in the Microsoft Cloud Partner Program.

Your migration and governance solution for Microsoft 365. ShareGate helps your teams simplify tenant migrations, get Copilot-ready, and take control of Microsoft 365 governance.

Nasuni is a leading unstructured data platform for enterprises where file data is mission-critical for both people and AI. We power the operational file layer where work happens — helping organizations manage, protect, and activate data so teams can work smarter, reduce costs, and operate securely without limits. Visit nasuni.com to learn more.

Would you like to become the irreplaceable Microsoft 365 resource for your organization? Let us know!

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Welcome to the Microsoft Cloud IT Podcast!

The weekly newsletter to accompany our podcast about Microsoft 365 and Azure. Scott and Ben are a couple of IT Pros that with a long history with Microsoft products. Recently Ben focuses primarily on Microsoft 365 but does a fair amount in Azure, and Scott spends most of his time in Azure, but with a history in SharePoint and Microsoft 365 still enjoys that side of things as well. We started this podcast over 5 years ago and continue to enjoy chatting weekly about various topics and technically in Microsoft 365 and Azure, specifically as it relates to IT Pros.

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